Histone modifications for human epigenome analysis
نویسندگان
چکیده
منابع مشابه
The Dynamic Epigenome - Analysis of the Distribution of Histone Modifications
There is a genome in a cell, as everyone knows, but there is also an epigenome. The epigenome regulates the transcription of the underlying genome. In the last decade, it was discovered that the epigenome state and its regulation are important for differentiation and development. Diseases were identified which are caused by errors in the epigenome state and its regulation. Therefore, several st...
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Maydup ML, Antonietta M, Guiamet JJ, Graciano C, Lopez JR, Tambussi EA. 2010. The contribution of ear photosynthesis to grain filling in bread wheat (Triticum aestivum L.). Field Crops Research 119, 48–58. Motzo R, Giunta F. 2002. Awnedness affects grain yield and kernel weight in near-isogenic lines of durum wheat. Australian Journal of Agricultural Research 53, 1285–1293. Rebetzke GJ, Bonnett...
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The global diabetes epidemic poses a major challenge. Epigenetic events contribute to the etiology of diabetes; however, the lack of epigenomic analysis has limited the elucidation of the mechanistic basis for this link. To determine the epigenetic architecture of human pancreatic islets we mapped the genome-wide locations of four histone marks: three associated with gene activation-H3K4me1, H3...
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Background: Vitrification has been usually used as an assisted reproductive technology in animals and humans. This method needs high concentrations of cryoprotectants that can be toxic with high cooling degrees. Then, vitrification could be change histone modifications such as methylation and acetylation can performance as regulatory controls of gene transcription. So, the purpose of the presen...
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Epigenetic mechanisms play an important role in regulating and stabilizing functional states of living cells. However, in spite of an increasing amount of experimental data, models of transcriptional regulation by epigenetic processes, in particular by histone modifications, are rather rare. In this article, we focus on epigenetic modes of transcriptional regulation based on histone modificatio...
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ژورنال
عنوان ژورنال: Journal of Human Genetics
سال: 2013
ISSN: 1434-5161,1435-232X
DOI: 10.1038/jhg.2013.66